St. Louis too tough for new office?

I've heard this too many times.  St. Louis does have a repetition for being too tough for opening new offices and operations.  It does have a Midwestern flavor but in Jim Durbin's article, "St. Louis: More Than You Expect", it's pointed out that networking is required.  There are differences in doing business here, but I've had offices in many different cities including Minneapolis, Austin and Dallas and trust me, all three are VERY different, even though two are in the same state. 

I urge new companies to take a hard look at St. Louis but realize, just as in many cities, hire some good local talent and make a real commitment.  You'll see it paid back many times.